Kocitaf For PEP and PrEP

Kocitaf is a combination medication used for HIV prevention and post-exposure prophylaxis (PEP). It contains three antiretroviral agents that work together to block HIV replication at multiple stages, making it an effective tool for individuals at risk of HIV exposure. At WellMed Bangkok Clinic, Kocitaf is available as part of our trusted HIV prevention and emergency care services.

Kocitaf is an antiretroviral combination tablet used primarily for PEP (post-exposure prophylaxis) and sometimes as PrEP (pre-exposure prophylaxis). It is prescribed for individuals who may have been exposed to HIV through unprotected sex, needle sharing, or other high-risk contact.

Each Kocitaf tablet contains:

• Dolutegravir: An integrase inhibitor that blocks HIV from integrating into the body’s DNA.

• Emtricitabine and Tenofovir Alafenamide Fumarate: Nucleoside reverse transcriptase inhibitors (NRTIs) that interfere with the virus’s ability to replicate.

Kocitaf is most effective when started within 72 hours of potential exposure and must be taken once daily for a full 28-day course.

How It Works

Kocitaf works by disrupting two critical stages of the HIV replication process:

1. Dolutegravir prevents the virus from integrating its genetic material into human cells.

2. Emtricitabine and Tenofovir block reverse transcription, a step where the virus makes copies of its DNA.

By halting replication early, Kocitaf gives the immune system a critical advantage, significantly reducing the risk of HIV infection when taken correctly and promptly.

Who Should Use It?

Kocitaf may be prescribed to individuals who:

• Have had unprotected sex with a potentially HIV-positive partner

• Have shared needles or injection equipment

• Were exposed to blood or bodily fluids in a medical or occupational setting

• Want to use PrEP as a preventive strategy in ongoing high-risk environments

A consultation at WellMed Bangkok Clinic is required to assess your exposure risk and determine if Kocitaf is the appropriate option.

Safety Information

• Contraindications: Not suitable for those allergic to any of the active ingredients. Always consult a doctor before use.

• Drug Interactions: May interact with anticonvulsants, antibiotics, or other HIV medications. Inform your doctor of all medications being taken.

• Side Effects: Common side effects may include headache, fatigue, nausea, or diarrhea. Serious side effects are rare but should be reported immediately.

• Precautions: Adherence is essential. Missing doses or stopping early can reduce effectiveness and increase the risk of HIV infection.

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