Amoxicillin + Clavulanic Acid

Amoxicillin + Clavulanic Acid is a combination prescription antibiotic used to treat a variety of bacterial infections. It combines amoxicillin, a penicillin-class antibiotic, with clavulanic acid, a beta-lactamase inhibitor that enhances its effectiveness against resistant bacteria. At WellMed Bangkok Clinic, this medication is prescribed for conditions that require a broader antibiotic spectrum to ensure effective treatment.

This medication is a broad-spectrum antibiotic combination. Amoxicillin works by killing bacteria, while clavulanic acid prevents certain bacteria from inactivating the antibiotic. This makes the drug especially effective against antibiotic-resistant strains.

It is commonly prescribed for:

• Respiratory tract infections such as bronchitis, sinusitis, and pneumonia

• Ear infections (otitis media)

• Urinary tract infections (UTIs)

• Skin and soft tissue infections

• Dental infections

• Gastrointestinal tract infections

• In some cases, meningitis or more serious infections

How It Works

Amoxicillin disrupts bacterial cell wall formation, leading to bacterial death.
Clavulanic acid inhibits beta-lactamase enzymes, which are produced by certain bacteria to resist penicillin antibiotics.

This dual action allows for more effective treatment, especially in infections where standard amoxicillin might fail.

Who Should Use It?

This medication may be suitable for:

• Adults and children diagnosed with bacterial infections

• Patients previously unresponsive to regular amoxicillin

• Cases requiring broad antibiotic coverage

Your doctor at WellMed Bangkok Clinic will determine the suitability based on your symptoms, medical history, and any recent antibiotic use.

Safety Information

• Contraindications: Not suitable for those with allergies to penicillin or cephalosporins, or individuals with a history of liver problems after antibiotic use.

• Drug Interactions: May interact with anticoagulants, allopurinol, and methotrexate.

• Side Effects: May include diarrhea, nausea, skin rash, or mild allergic reactions. Severe allergic responses are rare.

• Precautions: Take with food to reduce stomach upset. Complete the full course to avoid antibiotic resistance.

​